Hongjie Dai
Stanford University
H-index: 210
North America-United States
Description
Hongjie Dai, With an exceptional h-index of 210 and a recent h-index of 129 (since 2020), a distinguished researcher at Stanford University, specializes in the field of chemistry, materials science, physics, nanotechnology.
His recent articles reflect a diverse array of research interests and contributions to the field:
Proteoliposome-based ZnT8 self-antigen for type 1 diabetes diagnosis
Designing gelatin microgels by moderate transglutaminase crosslinking: Improvement in interface properties
Calcium-chelating peptides from rabbit bone collagen: characterization, identification and mechanism elucidation
Rechargeable Li/Cl2 Battery Down to −80 °C
In vivo NIR-II fluorescence imaging for biology and medicine
Intratumor injected gold molecular clusters for NIR-II imaging and cancer therapy
4D printing of betanin/gelatin/nano-chitin complexes-functionalized surimi via disulfide bonds, and its applicability in dysphagia diets
Sustainable and one-pot fabrication of peptide chelated calcium from fish scale hydrolysates
Professor Information
University | Stanford University |
---|---|
Position | Professor of chemistry |
Citations(all) | 247397 |
Citations(since 2020) | 67115 |
Cited By | 217878 |
hIndex(all) | 210 |
hIndex(since 2020) | 129 |
i10Index(all) | 507 |
i10Index(since 2020) | 393 |
University Profile Page | Stanford University |
Research & Interests List
chemistry
materials science
physics
nanotechnology
Top articles of Hongjie Dai
Proteoliposome-based ZnT8 self-antigen for type 1 diabetes diagnosis
Methods of detecting ZNT8 antibodies in serum are described. The methods include proteoliposomes comprising a transmembrane domain (TMD) and a cytosolic domain (CTD) of ZnT8 proteins exposed on the exterior of the proteoliposome; serum comprising antibodies targeting the ZnT8 proteins; and labelled captured autoantibodies that bind to ZnT8 antibodies.
Published Date
2024/2/6
Designing gelatin microgels by moderate transglutaminase crosslinking: Improvement in interface properties
In this study, gelatin microgels with various crosslinking degrees were facilely fabricated through moderate transglutaminase (TGase) crosslinking. The influences of crosslinking degree on the surface and interface properties of gelatin microgels were investigated. Furthermore, the influence on the stability of gelatin microgels emulsions was also explored. The crosslinking degree of gelatin microgels was gradually increased from 1.85% to 12.25% and positively correlated with the addition amount of TGase. With the increase of crosslinking degree, the high molecular weight components in gelatin microgels increased, and the wettability (32°–81°) and surface hydrophobicity of gelatin microgels gradually increased. The interfacial protein content also increased with the increase of crosslinking degree and reached equilibrium as the crosslinking degree exceeded 6.85%. The results of interfacial dynamic adsorption …
Authors
Hongjie Dai,Mengsi Xia,Xin Feng,Liang Ma,Hai Chen,Hankun Zhu,Yong Yu,Hongxia Wang,Yuhao Zhang
Journal
Food Hydrocolloids
Published Date
2024/4/1
Calcium-chelating peptides from rabbit bone collagen: characterization, identification and mechanism elucidation
This study aimed to characterize and identify calcium-chelating peptides from rabbit bone collagen and explore the underlying chelating mechanism. Collagen peptides and calcium were extracted from rabbit bone by instant ejection steam explosion (ICSE) combined with enzymatic hydrolysis, followed by chelation reaction to prepare rabbit bone peptide-calcium chelate (RBCP-Ca). The chelating sites were further analyzed by liquid chromatography-tandem mass (LC-MS/MS) spectrometry while the chelating mechanism and binding modes were investigated. The structural characterization revealed that RBCP successfully chelated with calcium ions. Furthermore, LC-MS/MS analysis indicated that the binding sites included both acidic amino acids (Asp and Glu) and basic amino acids (Lys and Arg). Interestingly, three binding modes, namely Inter-Linking, Loop-Linking and Mono-Linking were for the first time found …
Authors
Fuhuan Yuan,Yu Fu,Liang Ma,Hankun Zhu,Yong Yu,Xin Feng,Yi Sun,Hongjie Dai,Xin Liu,Zhengfang Liu,Yuhao Zhang
Journal
Food Science and Human Wellness
Published Date
2024/5/1
Rechargeable Li/Cl2 Battery Down to −80 °C
Low temperature rechargeable batteries are important to life in cold climates, polar/deep‐sea expeditions, and space explorations. Here, this work reports 3.5–4 V rechargeable lithium/chlorine (Li/Cl2) batteries operating down to −80 °C, employing Li metal negative electrode, a novel carbon dioxide (CO2) activated porous carbon (KJCO2) as the positive electrode, and a high ionic conductivity (≈5–20 mS cm−1 from −80 °C to room‐temperature) electrolyte comprised of aluminum chloride (AlCl3), lithium chloride (LiCl), and lithium bis(fluorosulfonyl)imide (LiFSI) in low‐melting‐point (−104.5 °C) thionyl chloride (SOCl2). Between room‐temperature and −80 °C, the Li/Cl2 battery delivers up to ≈29 100–4500 mAh g−1 first discharge capacity (based on carbon mass) and a 1200–5000 mAh g−1 reversible capacity over up to 130 charge–discharge cycles. Mass spectrometry and X‐ray photoelectron spectroscopy …
Authors
Peng Liang,Guanzhou Zhu,Cheng‐Liang Huang,Yuan‐Yao Li,Hao Sun,Bin Yuan,Shu‐Chi Wu,Jiachen Li,Feifei Wang,Bing‐Joe Hwang,Hongjie Dai
Journal
Advanced Materials
Published Date
2024/2
In vivo NIR-II fluorescence imaging for biology and medicine
Owing to reduced light scattering and tissue autofluorescence, in vivo fluorescence imaging in the 1,000–3,000-nm near-infrared II (NIR-II) spectral range can afford non-invasive imaging at depths of millimetres within biological tissue. Infrared fluorescent probes labelled with antibodies or other targeting ligands also enable NIR-II molecular imaging at the single-cell level. Here we present recent developments in the design of fluorophores and probes emitting in the NIR-II window based on organic synthesis and nanoscience approaches. We also review advances in NIR-II wide-field and microscopy imaging modalities, with a focus on preclinical imaging and promising clinical translation case studies. Finally, we outline current issues and challenges for the wider adoption of NIR-II imaging in biomedical research and clinical imaging.
Authors
Feifei Wang,Yeteng Zhong,Oliver Bruns,Yongye Liang,Hongjie Dai
Published Date
2024/3/4
Intratumor injected gold molecular clusters for NIR-II imaging and cancer therapy
Surgical resections of solid tumors guided by visual inspection of tumor margins have been performed for over a century to treat cancer. Near-infrared (NIR) fluorescence labeling/imaging of tumor in the NIR-I (800 to 900 nm) range with systemically administrated fluorophore/tumor-targeting antibody conjugates have been introduced to improve tumor margin delineation, tumor removal accuracy, and patient survival. Here, we show Au25 molecular clusters functionalized with phosphorylcholine ligands (AuPC, ~2 nm in size) as a preclinical intratumorally injectable agent for NIR-II/SWIR (1,000 to 3,000 nm) fluorescence imaging-guided tumor resection. The AuPC clusters were found to be uniformly distributed in the 4T1 murine breast cancer tumor upon intratumor (i.t.) injection. The phosphocholine coating afforded highly stealth clusters, allowing a high percentage of AuPC to fill the tumor interstitial fluid space …
Authors
Ani Baghdasaryan,Haoran Liu,Fuqiang Ren,RuSiou Hsu,Yingying Jiang,Feifei Wang,Mengzhen Zhang,Lilit Grigoryan,Hongjie Dai
Journal
Proceedings of the National Academy of Sciences
Published Date
2024/1/30
4D printing of betanin/gelatin/nano-chitin complexes-functionalized surimi via disulfide bonds, and its applicability in dysphagia diets
Betanin/gelatin/nano-chitin complexes were fabricated to functionalize surimi for 4D printing based on the pH responsiveness of betanin, and the application of functionalized surimi was investigated in terms of dysphagia diets. Gelatin and nano-chitin in synergy could protect betanin against heat and UV irradiation by forming hydrogen bonds and electrostatic interactions (CIELab, DSC, XRD, FTIR and TEM). The further functionalized surimi with betanin/gelatin/nano-chitin complexes exhibited low heating loss, heat chromatic aberration, superior thermal stability and compact microstructure (TGA, and SEM). Rheological tests indicated that betanin/gelatin/nano-chitin complexes could reduce the strength of interaction and form new interaction with surimi protein and promoted the surimi to have great shearing-thinning performance, excellent strain deformation resistance, low frequency dependence and great …
Authors
Juncheng Zhu,Yuxin Yang,Shihao Qiao,Hongjie Dai,Hai Chen,Yu Fu,Liang Ma,Hongxia Wang,Yuhao Zhang
Journal
Food Hydrocolloids
Published Date
2024/2/27
Sustainable and one-pot fabrication of peptide chelated calcium from fish scale hydrolysates
Fish scales, considered as low-value by-products, contain peptides and hydroxyapatite that can be applied to produce peptide chelated calcium directly. This study developed a sustainable and one-pot fabrication method for the peptide-chelated calcium from fish scale hydrolysates (FSP-Ca). During pepsin hydrolysis, the releases of peptides (FSP), calcium, and phosphate from fish scales occurred simultaneously, and the chelation was also effectively performed. After a 6-h hydrolysis, the yield of FSP was 46.18%, and the dissolution rate of calcium was 49.53%. Under the optimal conditions (pH 7, chelation time of 25 min, and chelation temperature of 48 °C), a high chelation rate of 86.16% was obtained, with a calcium content of 81.8 mg/g. The results of UV absorption, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM) confirmed the successful …
Authors
Hongjie Dai,Yingnan Cao,Yu Fu,Mi Tang,Xin Feng,Liang Ma,Yuhao Zhang
Journal
Collagen and Leather
Published Date
2024/12
Professor FAQs
What is Hongjie Dai's h-index at Stanford University?
The h-index of Hongjie Dai has been 129 since 2020 and 210 in total.
What are Hongjie Dai's top articles?
The articles with the titles of
Proteoliposome-based ZnT8 self-antigen for type 1 diabetes diagnosis
Designing gelatin microgels by moderate transglutaminase crosslinking: Improvement in interface properties
Calcium-chelating peptides from rabbit bone collagen: characterization, identification and mechanism elucidation
Rechargeable Li/Cl2 Battery Down to −80 °C
In vivo NIR-II fluorescence imaging for biology and medicine
Intratumor injected gold molecular clusters for NIR-II imaging and cancer therapy
4D printing of betanin/gelatin/nano-chitin complexes-functionalized surimi via disulfide bonds, and its applicability in dysphagia diets
Sustainable and one-pot fabrication of peptide chelated calcium from fish scale hydrolysates
...
are the top articles of Hongjie Dai at Stanford University.
What are Hongjie Dai's research interests?
The research interests of Hongjie Dai are: chemistry, materials science, physics, nanotechnology
What is Hongjie Dai's total number of citations?
Hongjie Dai has 247,397 citations in total.