Daniel A Horke
Radboud Universiteit
H-index: 25
Europe-Netherlands
About Daniel A Horke
Daniel A Horke, With an exceptional h-index of 25 and a recent h-index of 18 (since 2020), a distinguished researcher at Radboud Universiteit, specializes in the field of Ultrafast Dynamics, gas-phase dynamics, photochemistry, laser spectroscopy.
His recent articles reflect a diverse array of research interests and contributions to the field:
New aerodynamic lens injector for single particle diffractive imaging
Preparation of tautomer-pure molecular beams by electrostatic deflection
Resolving non-equilibrium shape variations amongst millions of gold nanoparticles
Direct Observation of a Roaming Intermediate and Its Dynamics
High-throughput UV-photofragmentation studies of thymine and guanine
Photoelectron circular dichroism upon multiphoton ionization of a chiral alcohol
High-Throughput UV Photoionization and Fragmentation of Neutral Biomolecules as a Structural Fingerprint
Vaporization of Intact Neutral Biomolecules Using Laser-Based Thermal Desorption
Daniel A Horke Information
University | Radboud Universiteit |
---|---|
Position | ___ |
Citations(all) | 1917 |
Citations(since 2020) | 1215 |
Cited By | 1294 |
hIndex(all) | 25 |
hIndex(since 2020) | 18 |
i10Index(all) | 39 |
i10Index(since 2020) | 33 |
University Profile Page | Radboud Universiteit |
Daniel A Horke Skills & Research Interests
Ultrafast Dynamics
gas-phase dynamics
photochemistry
laser spectroscopy
Top articles of Daniel A Horke
New aerodynamic lens injector for single particle diffractive imaging
Authors
Nils Roth,Daniel A Horke,Jannik Lübke,Amit K Samanta,Armando D Estillore,Lena Worbs,Nicolai Pohlman,Kartik Ayyer,Andrew Morgan,Holger Fleckenstein,Martin Domaracky,Benjamin Erk,Christopher Passow,Jonathan Correa,Oleksandr Yefanov,Anton Barty,Saša Bajt,Richard A Kirian,Henry N Chapman,Jochen Küpper
Journal
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Published Date
2024/1/1
An aerodynamic lens injector was developed specifically for the needs of single-particle diffractive imaging experiments at free-electron lasers. Its design allows for quick changes of injector geometries and focusing properties in order to optimize injection for specific individual samples. Here, we present results of its first use at the FLASH free-electron-laser facility. Recorded diffraction patterns of polystyrene spheres are modeled using Mie scattering, which allowed for the characterization of the particle beam under diffractive-imaging conditions and yielded good agreement with particle-trajectory simulations. The complex refractive index of polystyrene at λ= 4. 5 nm was determined as m= 0. 976− 0. 001 i.
Preparation of tautomer-pure molecular beams by electrostatic deflection
Authors
Grite L Abma,Michael A Parkes,Daniel A Horke
Journal
The Journal of Physical Chemistry Letters
Published Date
2024/4/24
Tautomers are ubiquitous throughout chemistry and typically considered inseparable in solution. Yet (bio)chemical activity is highly tautomer-specific, with common examples being the amino and nucleic acids. While tautomers exist in an equilibrium in solution, in the cold environment of a molecular beam the barrier to tautomerization is typically much too high for interconversion, and tautomers can be considered separate species. Here we demonstrate the first separation of tautomers within a molecular beam and the production of tautomerically pure gas-phase samples. We show this for the 2-pyridone/2-hydroxypyridine system, an important structural motif in both uracil and cytosine. Spatial separation of the tautomers is achieved via electrostatic deflection in strong inhomogeneous fields. We furthermore collect tautomer-resolved photoelectron spectra using femtosecond multiphoton ionization. This paves the …
Resolving non-equilibrium shape variations amongst millions of gold nanoparticles
Authors
Zhou Shen,Salah Awel,Anton Barty,Richard Bean,Johan Bielecki,Martin Bergemann,Benedikt J Daurer,Tomas Ekeberg,Armando D Estillore,Hans Fangohr,Klaus Giewekemeyer,Mark S Hunter,Mikhail Karnevskiy,Richard A Kirian,Henry Kirkwood,Yoonhee Kim,Jayanath Koliyadu,Holger Lange,Romain Letrun,Jannik Lübke,Abhishek Mall,Thomas Michelat,Andrew J Morgan,Nils Roth,Amit K Samanta,Tokushi Sato,Marcin Sikorski,Florian Schulz,Patrik Vagovic,Tamme Wollweber,Lena Worbs,Paul Lourdu Xavier,Filipe RNC Maia,Daniel A Horke,Jochen Küpper,Adrian P Mancuso,Henry N Chapman,Kartik Ayyer,N Duane Loh
Journal
arXiv preprint arXiv:2401.04896
Published Date
2024/1/10
Nanoparticles, exhibiting functionally relevant structural heterogeneity, are at the forefront of cutting-edge research. Now, high-throughput single-particle imaging (SPI) with x-ray free-electron lasers (XFELs) creates unprecedented opportunities for recovering the shape distributions of millions of particles that exhibit functionally relevant structural heterogeneity. To realize this potential, three challenges have to be overcome: (1) simultaneous parametrization of structural variability in real and reciprocal spaces; (2) efficiently inferring the latent parameters of each SPI measurement; (3) scaling up comparisons between structural models and XFEL-SPI measurements. Here, we describe how we overcame these three challenges to resolve the non-equilibrium shape distributions within millions of gold nanoparticles imaged at the European XFEL. These shape distributions allowed us to quantify the degree of asymmetry in these particles, discover a relatively stable `shape envelope' amongst nanoparticles, discern finite-size effects related to shape-controlling surfactants, and extrapolate nanoparticles' shapes to their idealized thermodynamic limit. Ultimately, these demonstrations show that XFEL SPI can help transform nanoparticle shape characterization from anecdotally interesting to statistically meaningful.
Direct Observation of a Roaming Intermediate and Its Dynamics
Authors
Russell Minns,Weronika Olimpia Razmus
Journal
Nature Chemistry
Published Date
2023
Chemical reactions are often characterised by their transition state, which defines the 16 critical geometry the molecule must pass through to move from reactants to products. 17 Roaming provides an alternative picture, where in a dissociation reaction the bond 18 breaking is frustrated, and a loosely bound intermediate is formed. Following bond 19 breaking the two partners are seen to roam around each other at distances of several 20 Angstroms, forming a loosely bound, and structurally ill-defined, intermediate that can 21 subsequently lead to reactive or unreactive collisions. Here we present a direct and 22 time-resolved experimental observation of roaming. By measuring the photoelectron 23 spectrum of UV excited acetaldehyde with a femtosecond extreme ultraviolet pulse, 24 we captured spectral signatures of all of the key reactive structures including that 25 of the roaming intermediate. This provided a direct experimental measurement of 26 the roaming process and allowed us to identify the timescales by which the roaming 27 intermediate is formed and removed, and the electronic potentials upon which roaming 28 proceeds. 29
High-throughput UV-photofragmentation studies of thymine and guanine
Authors
Siwen Wang,Yerbolat Dauletyarov,Peter Krüger,Daniel A Horke
Journal
Physical Chemistry Chemical Physics
Published Date
2023
High-throughput photofragmentation studies of thymine and guanine were performed at 257 and 343 nm and for a wide range of ionisation laser intensities. Combining a continuous laser-based thermal desorption source with femtosecond multiphoton ionisation using a 50 kHz repetition rate laser allowed us to produce detailed 2D maps of fragmentation as a function of incident laser intensity. The fragmentation was distinctly soft, the parent ions being at least an order of magnitude more abundant than fragment ions. For thymine there was a single dominant fragmentation channel, which involves consecutive HNCO and CO losses. In contrast, for guanine there were several competing ones, the most probable channel corresponding to CH2N2 loss through opening of the pyrimidine ring. The dependence of parent ion abundance on the ionisation laser intensity showed that at 257 nm the ionisation of thymine is a 1 …
Photoelectron circular dichroism upon multiphoton ionization of a chiral alcohol
Authors
Peter Krüger,Michiel Balster,Bhargava Ram Niraghatam,Maurice HM Janssen,Daniel A Horke
Journal
arXiv preprint arXiv:2310.02893
Published Date
2023/10/4
We present the first photoelectron circular dichroism (PECD) measurements of chiral alcohols, and in particular 1-Phenylethanol, using multiphoton ionization at 400 nm. Observed PECD values were rather small at %, but could be reliably extracted using both hemispherical integration and Abel inversion approaches. Experimental uncertainties of % (2) were achieved with a collection time of around 2 hours. All experiments were conducted in a new compact spectrometer, featuring a continuous flow supersonic expansion and velocity-map imaging detection. The latter is crucial to extract reliable PECD values, as it allows discrimination of different features in the photoelectron spectrum, which exhibit different and opposing PECD signals. The use of a tabletop multiphoton universal ionization scheme is an important step towards a viable analytical chiral spectrometer based on PECD.
High-Throughput UV Photoionization and Fragmentation of Neutral Biomolecules as a Structural Fingerprint
Authors
Siwen Wang,Yerbolat Dauletyarov,Daniel A Horke
Journal
Molecules
Published Date
2023/6/28
We present UV photofragmentation studies of the structural isomers paracetamol, 3-Pyridinepropionic acid (3-PPIA) and (R)-(-)-2-Phenylglycine. In particular, we utilized a new laser-based thermal desorption source in combination with femtosecond multiphoton ionization at 343 nm and 257 nm. The continuous nature of our molecule source, combined with the 50 kHz repetition rate of the laser, allowed us to perform these experiments at high throughput. In particular, we present detailed laser intensity dependence studies at both wavelengths, producing 2D mass spectra with highly differential information about the underlying fragmentation processes. We show that UV photofragmentation produces highly isomer-specific mass spectra, and assign all major fragmentation pathways observed. The intensity-dependence measurements, furthermore, allowed us to evaluate the appearance intensities for each fragmentation channel, which helped to distinguish competing from consecutive fragmentation pathways.
Vaporization of Intact Neutral Biomolecules Using Laser-Based Thermal Desorption
Authors
Yerbolat Dauletyarov,Siwen Wang,Daniel A Horke
Journal
Journal of the American Society for Mass Spectrometry
Published Date
2023/6/15
The production of a clean neutral molecular sample is a crucial step in many gas-phase spectroscopy and reaction dynamics experiments investigating neutral species. Unfortunately, conventional methods based on heating cannot be used with most nonvolatile biomolecules due to their thermal instability. In this paper, we demonstrate the application of laser-based thermal desorption (LBTD) to produce neutral molecular plumes of biomolecules such as dipeptides and lipids. Specifically, we report mass spectra of glycylglycine, glycyl-l-alanine, and cholesterol obtained using LBTD vaporization, followed by soft femtosecond multiphoton ionization (fs-MPI) at 400 nm. For all molecules, the signal from the intact precursor ion was observed, highlighting the softness and applicability of the LBTD and fs-MPI approach. In more detail, cholesterol underwent hardly any fragmentation. Both dipeptides fragmented …
2023 Horke OpenScienceLab Motorized Kinematic Mount
Authors
DA Horke,A Caballo Zulueta
Published Date
2023
Design files and instructions to turn a standard kinematic mount into a motorized kinematic mount
Optical Funnel to Guide and Focus Virus Particles for X-Ray Diffractive Imaging
Authors
Salah Awel,Sebastian Lavin-Varela,Nils Roth,Daniel A Horke,Andrei V Rode,Richard A Kirian,Jochen Küpper,Henry N Chapman
Journal
Physical Review Applied
Published Date
2022/4/22
Photophoretic forces are induced when light causes a net momentum exchange between a particle and a surrounding gas. Such forces have been shown to be a robust means for trapping and guiding particles in air over long distances. Here, we apply the concept of an optical funnel for the delivery of bioparticles to the focus of an x-ray free-electron laser (XFEL) for femtosecond x-ray diffractive imaging. We provide the experimental demonstration of transversely compressing a high-speed beam of aerosolized viruses via photophoretic forces in a low-pressure gas environment. Relative temperature gradients induced on the viruses by the laser are estimated via particle-velocimetry measurements. The results demonstrate the potential for an optical funnel to improve particle-delivery efficiency in XFEL imaging and spectroscopy.
Unsupervised learning approaches to characterizing heterogeneous samples using X-ray single-particle imaging
Authors
Yulong Zhuang,Salah Awel,Anton Barty,Richard Bean,Johan Bielecki,Martin Bergemann,Benedikt J Daurer,Tomas Ekeberg,Armando D Estillore,Hans Fangohr,Klaus Giewekemeyer,Mark S Hunter,Mikhail Karnevskiy,Richard A Kirian,Henry Kirkwood,Yoonhee Kim,Jayanath Koliyadu,Holger Lange,Romain Letrun,Jannik Lübke,Abhishek Mall,Thomas Michelat,Andrew J Morgan,Nils Roth,Amit K Samanta,Tokushi Sato,Zhou Shen,Marcin Sikorski,Florian Schulz,John CH Spence,Patrik Vagovic,Tamme Wollweber,Lena Worbs,P Lourdu Xavier,Oleksandr Yefanov,Filipe RNC Maia,Daniel A Horke,Jochen Küpper,N Duane Loh,Adrian P Mancuso,Henry N Chapman,Kartik Ayyer
Journal
IUCrJ
Published Date
2022/3/1
One of the outstanding analytical problems in X-ray single-particle imaging (SPI) is the classification of structural heterogeneity, which is especially difficult given the low signal-to-noise ratios of individual patterns and the fact that even identical objects can yield patterns that vary greatly when orientation is taken into consideration. Proposed here are two methods which explicitly account for this orientation-induced variation and can robustly determine the structural landscape of a sample ensemble. The first, termed common-line principal component analysis (PCA), provides a rough classification which is essentially parameter free and can be run automatically on any SPI dataset. The second method, utilizing variation auto-encoders (VAEs), can generate 3D structures of the objects at any point in the structural landscape. Both these methods are implemented in combination with the noise-tolerant expand–maximize …
Disentangling Multiphoton Ionization and Dissociation Channels in Molecular Oxygen Using Photoelectron–Photoion Coincidence Imaging
Authors
Ana Caballo,Anders JTM Huits,David H Parker,Daniel A Horke
Journal
The Journal of Physical Chemistry A
Published Date
2022/12/21
Multiphoton excitation of molecular oxygen in the 392–408 nm region is studied using a tunable femtosecond laser coupled with a double velocity map imaging photoelectron–photoion coincidence spectrometer. The laser intensity is held at ≤∼1 TW/cm2 to ensure excitation in the perturbative regime, where the possibility of resonance enhanced multiphoton ionization (REMPI) can be investigated. O2+ production is found to be resonance enhanced around 400 nm via three-photon excitation to the e′3Δu(v = 0) state, similar to results from REMPI studies using nanosecond dye lasers. O+ production reaches 7% of the total ion yield around 405 nm due to two processes: autoionization following five-photon excitation of O2, producing O2+(X(v)) in a wide range of vibrational states followed by two- or three-photon dissociation, or six-photon excitation to a superexcited O2** state followed by neutral dissociation and …
Sub-3-nm Resolution 3D Diffractive Imaging of Anisotropic Gold Nanoparticles with Millions of Patterns using MHz XFEL Pulses
Authors
P Lourdu Xavier,Kartik Ayyer,Johan Bielecki,Zhou Shen,Benedikt J Daurer,Amit K Samanta,Salah Awel,Richard Bean,Anton Barty,Martin Bergemann
Published Date
2022
We have demonstrated the collection of more than ten-million diffraction patterns from 4 different AuNP samples with the MHz XFEL pulses at the EuXFEL and achieved sub 3-nm resolution 3D reconstrcution. This is a significant milestone in XFEL-SPI—thus illuminating a way to image biomacromolecules at high resolution.
Comparing pulsed and continuous laser-induced acoustic desorption (LIAD) as sources for intact biomolecules
Authors
Siwen Wang,Grite L Abma,Peter Krüger,Andre van Roij,Michiel Balster,Niek Janssen,Daniel A Horke
Journal
The European Physical Journal D
Published Date
2022/7
A major obstacle to the gas-phase study of larger (bio)molecular systems is the vaporisation step, that is, the introduction of intact sample molecules into the gas-phase. A promising approach is the use of laser-induced acoustic desorption (LIAD) sources, which have been demonstrated using both nanosecond pulsed and continuous desorption lasers. We directly compare here both approaches for the first time under otherwise identical conditions using adenine as a prototypical biological molecule, and study the produced molecular plumes using femtosecond multiphoton ionisation. We observe different desorption mechanisms at play for the two different desorption laser sources; however, we find no evidence in either case that the desorption process leads to fragmentation of the target molecule unless excessive desorption energy is applied. This makes LIAD a powerful approach for techniques that require high …
Mapping Complex Photochemical Reactions Using Femtosecond Uv-pump Xuv-probe Photoelectron Spectroscopy
Authors
Daniel Horke
Published Date
2022/6/21
Abstract\begin {wrapfigure}{r}{0pt}\includegraphics [scale= 0.25]{HHG_TRPES. eps}\caption {Time-resolved photoelectron spectroscopy of\chem {CS_2} dissociation. XUV probe pulses allow us to map all intermediate and final states.}\end {wrapfigure} Time-resolved photoelectron spectroscopy has emerged as one of the premier tools to study the complex coupled motion of electrons and nuclei that underlies ultrafast photochemical processes. To study the entire reaction pathway from reactants through intermediates to products, however, requires sufficiently energetic photons to ionise all species involved. The advent of high-flux high-harmonic generation sources now puts this within reach, and we present here femtosecond photoelectron spectroscopy studies using UV-pump XUV-probe pulses. We used this approach to probe the dynamics of dissociating\chem {CS_2} molecules across the entire reaction pathway upon excitation, Figure 1. Dissociation occurs either in the initially excited singlet manifold or, via intersystem crossing, in the triplet manifold. Both product channels are monitored and we show that, despite being more rapid, the singlet dissociation is the minor product and that triplet state products dominate the final yield. We will also show first results of our recent UV-pump XUV-probe studies of acetaldehyde photodissociation and aim to unravel the complex competing direct and roaming dissociation channels.
Single-Color Isomer-Resolved Spectroscopy
Authors
Grite L Abma,Dries Kleuskens,Siwen Wang,Michiel Balster,Andre van Roij,Niek Janssen,Daniel A Horke
Journal
The Journal of Physical Chemistry A
Published Date
2022/6/1
Structural isomers, such as conformers or tautomers, are of significant importance across chemistry and biology, as they can have different functionalities. In gas-phase experiments using molecular beams, formation of many different isomers cannot be prevented, and their presence significantly complicates the assignment of spectral lines. Current isomer-resolved spectroscopic techniques heavily rely on theoretical calculations or make use of elaborate double-resonance schemes. We show here that isomer-resolved spectroscopy can also be performed using a single tunable laser. In particular, we demonstrate single-color isomer-resolved spectroscopy by utilizing electrostatic deflection to spatially separate the isomers. We show that for 3-aminophenol we can spatially separate the syn and anti conformers and use these pure samples to perform high-resolution REMPI spectroscopy, making the assignment of …
3D diffractive imaging of nanoparticle ensembles using an x-ray laser
Authors
Kartik Ayyer,P Lourdu Xavier,Johan Bielecki,Zhou Shen,Benedikt J Daurer,Amit K Samanta,Salah Awel,Richard Bean,Anton Barty,Martin Bergemann,Tomas Ekeberg,Armando D Estillore,Hans Fangohr,Klaus Giewekemeyer,Mark S Hunter,Mikhail Karnevskiy,Richard A Kirian,Henry Kirkwood,Yoonhee Kim,Jayanath Koliyadu,Holger Lange,Romain Letrun,Jannik Lübke,Thomas Michelat,Andrew J Morgan,Nils Roth,Tokushi Sato,Marcin Sikorski,Florian Schulz,John CH Spence,Patrik Vagovic,Tamme Wollweber,Lena Worbs,Oleksandr Yefanov,Yulong Zhuang,Filipe RNC Maia,Daniel A Horke,Jochen Küpper,N Duane Loh,Adrian P Mancuso,Henry N Chapman
Journal
Optica
Published Date
2021/1/20
Single particle imaging at x-ray free electron lasers (XFELs) has the potential to determine the structure and dynamics of single biomolecules at room temperature. Two major hurdles have prevented this potential from being reached, namely, the collection of sufficient high-quality diffraction patterns and robust computational purification to overcome structural heterogeneity. We report the breaking of both of these barriers using gold nanoparticle test samples, recording around 10 million diffraction patterns at the European XFEL and structurally and orientationally sorting the patterns to obtain better than 3-nm-resolution 3D reconstructions for each of four samples. With these new developments, integrating advancements in x-ray sources, fast-framing detectors, efficient sample delivery, and data analysis algorithms, we illuminate the path towards sub-nanometer biomolecular imaging. The methods developed here …
Charge-state distribution of aerosolized nanoparticles
Authors
Jannik Lübke,Nils Roth,Lena Worbs,Daniel A Horke,Armando D Estillore,Amit K Samanta,Jochen Küpper
Journal
The Journal of Physical Chemistry C
Published Date
2021/11/16
In single-particle imaging experiments, beams of individual nanoparticles are exposed to intense pulses of X-rays from free-electron lasers to record diffraction patterns of single, isolated molecules. The reconstruction for structure determination relies on signals from many identical particles. Therefore, well-defined-sample delivery conditions are desired in order to achieve sample uniformity, including avoidance of charge polydispersity. We have observed charging of 220 nm polystyrene particles in an aerosol beam created by a gas-dynamic virtual nozzle focusing technique, without intentional charging of the nanoparticles. Here, we present a deflection method for detecting and characterizing the charge states of a beam of aerosolized nanoparticles. Our analysis of the observed charge-state distribution using optical light-sheet localization microscopy and quantitative particle trajectory simulations is consistent with …
Femtosecond 2 + 1 Resonance-Enhanced Multiphoton Ionization Spectroscopy of the C-State in Molecular Oxygen
Authors
Ana Caballo,Anders JTM Huits,Arno Vredenborg,Michiel Balster,David H Parker,Daniel A Horke
Journal
The Journal of Physical Chemistry A
Published Date
2021/10/11
Coincidence electron-cation imaging is used to characterize the multiphoton ionization of O2 via the v = 4,5 levels of the 3s(3Πg) Rydberg state. A tunable 100 fs laser beam operating in the 271–263 nm region is found to cause a nonresonant ionization across this wavelength range, with an additional resonant ionization channel only observed when tuned to the 3Πg(v = 5) level. A distinct 3s → p wave character is observed in the photoelectron angular distribution for the v = 5 channel when on resonance.
Time resolved detection of the S (1D) product of the UV induced dissociation of CS2
Authors
Emily M Warne,Adam D Smith,Daniel A Horke,Emma Springate,Alfred JH Jones,Cephise Cacho,Richard T Chapman,Russell S Minns
Journal
The Journal of Chemical Physics
Published Date
2021/1/21
The products formed following the photodissociation of UV (200 nm) excited CS 2 are monitored in a time resolved photoelectron spectroscopy experiment using femtosecond XUV (21.5 eV) photons. By spectrally resolving the electrons, we identify separate photoelectron bands related to the CS 2+ hν→ S (1 D)+ CS and CS 2+ hν→ S (3 P)+ CS dissociation channels, which show different appearance and rise times. The measurements show that there is no delay in the appearance of the S (1 D) product contrary to the results of Horio et al.[J. Chem. Phys. 147, 013932 (2017)]. Analysis of the photoelectron yield associated with the atomic products allows us to obtain a S (3 P)/S (1 D) branching ratio and the rate constants associated with dissociation and intersystem crossing rather than the effective lifetime observed through the measurement of excited state populations alone.
Daniel A Horke FAQs
What is Daniel A Horke's h-index at Radboud Universiteit?
The h-index of Daniel A Horke has been 18 since 2020 and 25 in total.
What are Daniel A Horke's top articles?
The articles with the titles of
New aerodynamic lens injector for single particle diffractive imaging
Preparation of tautomer-pure molecular beams by electrostatic deflection
Resolving non-equilibrium shape variations amongst millions of gold nanoparticles
Direct Observation of a Roaming Intermediate and Its Dynamics
High-throughput UV-photofragmentation studies of thymine and guanine
Photoelectron circular dichroism upon multiphoton ionization of a chiral alcohol
High-Throughput UV Photoionization and Fragmentation of Neutral Biomolecules as a Structural Fingerprint
Vaporization of Intact Neutral Biomolecules Using Laser-Based Thermal Desorption
...
are the top articles of Daniel A Horke at Radboud Universiteit.
What are Daniel A Horke's research interests?
The research interests of Daniel A Horke are: Ultrafast Dynamics, gas-phase dynamics, photochemistry, laser spectroscopy
What is Daniel A Horke's total number of citations?
Daniel A Horke has 1,917 citations in total.